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The relationship of centralized pain in fibromyalgia syndrome with sleep, fatigue and quality of life

Abstract Objectives The aim of this study was to examine the central role of pain in patients’ lives by evaluating the relationship between the centralization of pain and clinical and functional parameters. Methods Adult patients aged 18–70 diagnosed with FM were included in the study. The Fibromyalgia Impact Questionnaire (FIQ) was used to assess the severity of FM, and the Centrality of Pain Scale (COPS) was used to assess pain centralization. The European Quality of Life Scale 5 Dimension (EQ-5D) assessed quality of life, the Jenkins Sleep Scale (JSS-TR) sleep, and the Beck Depression Inventory (BDI) depression.Spearman correlation coefficient (rho) was used to examine the relationship between COPS scores and other parameters, and p < .05 was considered significant. Results One hundred and sixty-five FM patients (143 female) were included in the study. The mean age of the patients was 43.7 ± 10.1 years, and the mean disease duration was 4.8 ± 7.8 years. Centrality of pain was found to be related to FIQ (rho = 0.59, p = .0005), EQ-5D (rho = −0.53, p = .0005), JSS-TR (rho = 0.43, p = .0005), and BDI (rho = 0.41, p = .0005). Conclusion Centralization of pain in FM was more common in patients with high disease severity, poor quality of life, and sleep and depression problems.


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